SEECH v. COMMISSIONER OF SOCIAL SECURITY, No. 2:2009cv00701 - Document 11 (W.D. Pa. 2010)

Court Description: MEMORANDUM OPINION denying 6 Plaintiff's Motion for Summary Judgment; and granting 8 Defendant's Motion for Summary Judgment as set forth more fully within. Signed by Judge Joy Flowers Conti on 7/30/10. (Attachments: # 1 website material referred to in footnote 4) (cal )

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SEECH v. COMMISSIONER OF SOCIAL SECURITY Doc. 11 Att. 1 Dilantin Page 1 of5 . Drugs.com Dilantin Generic Name: phenytoin (oral) (FEN i toyn) Brand names: Dilantin, Dilantin Infatabs, Dilantin-125, Phenytek, Phenytoin Sodium, Prompt, Di/antin Kapsea/s, Phenytoin Sodium, Prompt. Di-Phen What is Dilantin? Dilantin (phenytoin) is an anti-epileptic drug, also called an anticonvulsant It works by slowing down impulses in the brain that cause seizures. Epilepsy out of control? This clin research study may be an option to consider. www.StudyingEpilepsy.com Do You Have Epilepsy? Tilke surveys to compare your epilepsy to people like you. FI"ee l www.patientslikeme.com Levetiracetam Side Effect Seizures From Your Drug'? You May Have a Case! Ana polSchwa rtz .com/M y Ian -Seizuresl Dilantin is used to control seizures. It is not made to treat all types of seizures, and your doctor will determine if it is the right medication for you. Dilantin may also be used for other purposes not listed in this medication guide. Important information about Dilantin If you are taking Dilantin to prevent seizures, keep taking the medication even if you feel fine. You may have an increase in seizures if you stop taking Dilantin. Do not change your dose of Dilantin without your doctor's advice. Tell your doctor if the medication does not seem to work as well in treating your condition You may have thoughts about suicide while taking Dilantin. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments. Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depression, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself. Before taking Dilantin You should not use Dilantin if you are allergic to phenytoin. If you have any of these other conditions, you may need a dose adjustment or special tests: ¢ liver disease; ¢ porphyria; ¢ diabetes; or ¢ a vitamin D deficiency or any other condition that causes thinning of the bones. http://www.drugs.com/diiantin.html?printable=l 7/3012010 Dockets.Justia.com Dilantin Page 2 of5 You may have thoughts about suicide while taking Dilantin. Tell your doctor if you have new or worsening depression or suicidal thoughts during the first several months of treatment, or whenever your dose is changed. Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits. Do not miss any scheduled appointments. Patients of Asian ancestry may have a higher risk of developing a rare but serious skin reaction to Dilantin. Your doctor may recommend a blood test before you start the medication to determine your risk of this skin reaction. Dilantin can affect your blood sugar. If you are a diabetic, check your blood sugar regularly while you are taking this medication. FDA pregnancy category D. Do not use Dilantin without your doctor's consent if you are pregnant. It could harm the unborn baby. Dilantin may also not be as effective in reducing seizures if taken during pregnancy. Use effective birth control, and tell your doctor if you become pregnant during treatment. Although Dilantin might harm an unborn baby, having a seizure during pregnancy could harm both mother and baby. Follow your doctor's instructions about taking Dilantin while you are pregnant. Dilantin can make birth control pills less effective. Use a non-hormonal form of birth control (such as a condom or diaphragm with spermicide) to prevent an unintended pregnancy. Phenytoin can pass into breast milk and may harm a nursing baby. Do not use Dilantin without telling your doctor if you are breast-feeding a baby. How should I take Dilantin? Take Dilantin exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Do not crush, chew, break, or open an extended-release capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. Do not use any Dilantin capsule or tablet that has changed colors. Call your doctor for a new prescription. The chewable tablet may be chewed, broken, or crushed before swallowing, or it may be swallowed whole. Shake the Dilantin oral suspension (liquid) well just before you measure a dose. Measure the liquid with a special dose-measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one. To be sure Dilantin is helping your condition, your blood may need to be tested often. You may also need a blood test when switching from one form of phenytoin to another. Visit your doctor regularly. If you are taking Dilantin to treat seizures, keep taking the medication even if you feel fine. You may have an increase in seizures if you stop taking Dilantin. Follow your doctor's instructions. Do not change your dose of Dilantin without your doctor's advice. Tell your doctor if the medication does not seem to work as well in treating your condition. Wear a medical alert tag or carry an ID card stating that you take Dilantin. Any medical care provider who treats you should know that you are taking a seizure medication. Store at room temperature away from moisture, light, and heat. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled http;//www.drugs.com/dilantin.html?printable=l 7/30/2010 Dilantin Page 3 of 5 dose. Do not take extra medicine to make up the missed dose. What happens if I overdose? Seek emergency medical attentionor call the Poison Help line at 1-800-222-1222. An overdose of Dilantin can be fatal. Overdose symptoms may include twitching eye movements, slurred speech, loss of balance, tremor, muscle stiffness or weakness, nausea, vomiting, feeling light-headed, fainting, and slow or shallow breathing. What should I avoid while taking Dilantin? Drinking alcohol can increase some of the side effects of Dilantin, and can also increase your risk of seizure. Avoid taking antacids at the same time you take Dilantin. Antacids can make it harder for your body to absorb the medication. Dilantin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Dilantin side effects Get emergency medical help if you have any of these signs of an allergic reaction to Dilantin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, depreSSion, anxiety, or if you feel agitated, hostile, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself. Call your doctor at once if you have any of these serious side effects: ¢ swollen glands, easy bruising or bleeding, swollen or tender gums; ¢ fever, sore throat, and headache with a severe blistering, peeling, and red skin rash; ¢ the first sign of any skin rash, no matter how mild; ¢ confusion, hallucinations, unusual thoughts or behavior; ¢ slurred speech, loss of balance or coordination; ¢ tremor (uncontrolled shaking), restless muscle movements in your eyes, tongue, jaw, or neck; ¢ extreme thirst or hunger, urinating more than usual; ¢ loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); or ¢ changes in the shape of your face or lips. Less serious Dilantin side effects may include: ¢ mild skin rash or itching; ¢ dizziness, nervousness, sleep problems (insomnia); http://www.drugs.com/dilantin.html ?printable= 1 7/30/2010 Dilantin Page 4 of 5 ¢ nausea, vomiting, constipation; or ¢ headache, joint pain. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-S00-FDA-10SS. What other drugs will affect Dilantin? Drugs that can increase Dilantin levels in your blood include: ¢ stomach acid reducers such as cimetidine (Tagamet), ranitidine (Zantac), famotidine (Pepcid), or nizatidine (Axid); ¢ certain sedatives (such as Librium or Valium) or antidepressants (such as Prozac); ¢ estrogen hormone replacement; ¢ chlorpromazine (Thorazine), prochlorperazine (Compazine), thioridazine (Mellaril) and other phenothiazines; ¢ disulfiram (Antabuse); ¢ methylphenidate (Ritalin, Concerta, Daytrana); and ¢ sulfa drugs such as Septra or Bactrim. Drugs that can make Dilantin less effective in controlling seizures include carbamazepine (Tegretol, Epitol, Carbatrol), sucralfate (Carafate), and molindone (Moban). Other drugs that can interact with Dilantin include: ¢ phenobarbital (Luminal, Solfoton), valproic acid (Depakene) or divalproex sodium (Depakote); ¢ steroid medicines (prednisone and others); ¢ antidepressants such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine. Tofranil). paroxetine (Paxil). and others; ¢ antibiotics such as rifampin (Rimactane, Rifadin, Rifamate) or doxycycline (Doryx, Vibramycin. Adoxa. and others); ¢ digoxin (digitalis. Lanoxin). furosemide (Lasix); and ¢ theophylline (Elixophyllin, Theo-Dur, Theo-Bid, Theolair, Uniphyl). This list is not complete and there are many other medicines that can interact with Dilantin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you. Where can I get more information? ¢ Your pharmacist can provide more information about Dilantin. http://www.drugs.com/dilantin.html ?printable= 1 7/30/2010 Dilantin Page 50f5 ¢ Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. ¢ Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Copyright 1996-2010 Cerner Multum, Inc. Version: 1101. Revision Date: 03/30/20102:29:40 PM. htlp:llwww.drugs.com/dilantin.html?printable= 1 7/30/2010

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